President Barack Obama’s much-anticipated Cairo speech reflected a significant shift away from the ideological framework of militarism and unilateralism that shaped the Bush administration’s war-based policy toward the Arab and Muslim worlds. His "not Bush" focus was perhaps most sharply evident in his public denunciation of the Iraq War as a "war of choice." Obama’s call for a "new beginning" based on "the truth that America and Islam are not exclusive and need not be in competition" was followed by a move to shift the official U.S. discourse toward something closer to internationalism — particularly by pointing to parallels between historical (and some contemporary) grievances and treating them as equivalent. This included his reference to the U.S. "role in the overthrow of a democratically elected Iranian government," along with Iran’s "role in acts of hostage-taking and violence against U.S. troops and civilians."

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